FDA banned the production or sales of NMN as dietary supplements in the USA

Amazon is banning the sale of beta-nicotinamide mononucleotide (NMN) products, according to a letter from Amazon’s Restricted Products Team furnished by the Natural Products Association (NPA; Washington, D.C.). The letter told sellers that NMN products would be banned after March 13, 2023. In November of 2022, the U.S. Food and Drug Administration (FDA) determined that NMN was not a dietary ingredient, citing the drug preclusion clause of the Food, Drug and Cosmetic Act. As such, according to Amazon, if someone wants to sell NMN on Amazon, they must produce proof that it is approved by FDA for over-the-counter sales.

“This the first time in history that FDA reversed itself on an acknowledgement letter for a new dietary ingredient without a shred of evidence that safety was at risk,” he added. “It is setting a new precedent in that an announcement of Generally Recognized as Safe no longer constitutes evidence of the marketing of NMN as a food before the ingredient was authorized for investigation as a new drug.”